Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.
| Version: | 3.0.3 |
| Depends: | R (≥ 3.5.0) |
| Imports: | XML, httr, haplo.stats, parallel |
| Suggests: | knitr, rmarkdown |
| Published: | 2021-11-17 |
| DOI: | 10.32614/CRAN.package.BIGDAWG |
| Author: | Derek Pappas, Steve Mack, Jill Hollenbach |
| Maintainer: | Steve Mack <Steven.Mack at ucsf.edu> |
| BugReports: | https://github.com/IgDAWG/BIGDAWG/issues |
| License: | GPL (≥ 3) |
| URL: | http://tools.immunogenomics.org/, https://github.com/IgDAWG/BIGDAWG |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | BIGDAWG results |
| Reference manual: | BIGDAWG.html , BIGDAWG.pdf |
| Vignettes: |
BIGDAWG (source) GLSconvert (source) |
| Package source: | BIGDAWG_3.0.3.tar.gz |
| Windows binaries: | r-devel: BIGDAWG_3.0.3.zip, r-release: BIGDAWG_3.0.3.zip, r-oldrel: BIGDAWG_3.0.3.zip |
| macOS binaries: | r-release (arm64): BIGDAWG_3.0.3.tgz, r-oldrel (arm64): BIGDAWG_3.0.3.tgz, r-release (x86_64): BIGDAWG_3.0.3.tgz, r-oldrel (x86_64): BIGDAWG_3.0.3.tgz |
| Old sources: | BIGDAWG archive |
| Reverse imports: | pould |
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