| Type: | Package |
| Title: | Rcmdr Evidence Based Medicine Plug-in Package |
| Version: | 1.0-10 |
| Date: | 2015-09-30 |
| Author: | Daniel-Corneliu Leucuta <danny.ldc@gmail.com> |
| Maintainer: | Daniel-Corneliu Leucuta <danny.ldc@gmail.com> |
| Depends: | R (≥ 2.10), Rcmdr (≥ 1.7.0), epiR, abind |
| Description: | Rcmdr plug-in GUI extension for Evidence Based Medicine medical indicators calculations (Sensitivity, specificity, absolute risk reduction, relative risk, ...). |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| Packaged: | 2015-09-30 10:03:11 UTC; danny |
| NeedsCompilation: | no |
| Repository: | CRAN |
| Date/Publication: | 2015-10-01 11:13:32 |
Evidence Based Medicine Rcmdr Plug-In
Description
This package provides an Rcmdr GUI extension plug-in for Evidence Based Medicine calculations. The purpose of this GUI extension was to improve teaching in the use of Evidence Based Medicine calculations. The interface allows for computing diagnostic medical indicators: sensitivity, specificity, diagnostic accuracy, Youden's index, positive predictive value, negative predictive value, positive likelyhood ratio, negative likelyhood ratio, number needed to diagnose; prognosis medical indicators: relative risk, atributable risk, odds ratio; therapeutic medical indicators: absolute risk reduction, number needed to treat, relative risk reduction, relative risk, odds ratio. Also the interface allows computing the post-test probability from a pre-test probability and the likelyhood ratio.
The medical indicators are computed with epi.2by2.
For therapy indicators it offers results based AR, OR, RR with their confidence intervals. The following calculations are done to compute the therapeutic indicators:
ARR <- - AR (ARR CI lower bound =min(-AR$lower, -AR$upper), ARR CI upper bound =max(-AR$lower, - AR$upper))
NNT <- 1 / ARR (NNT CI lower bound =min(1/ARR.lower, 1/ARR.upper), NNT CI upper bound =max(1/ARR.lower, 1/ARR.upper))
if ARR.lower<0 then NNT.lower = NNT.upper and NNT.upper = inf
RR <- RR
OR <- OR
RRR <- 1 - RR (RRR CI lower bound =min(1-RR$lower, 1-RR$upper), RRR CI upper bound =max(1-RR$lower, 1-RR$upper))
Details
| Package: | RcmdrPlugin.EBM |
| Type: | Package |
| Version: | 1.0-2 |
| Date: | 2012-04-13 |
| License: | GPL (>= 2) |
| LazyLoad: | yes |
Author(s)
Daniel-Corneliu Leucuta
Maintainer: Daniel-Corneliu Leucuta <danny.ldc@gmail.com>
See Also
Internal RcmdrPlugin.EBM objects
Description
Internal RcmdrPlugin.EBM objects.
Details
These are not to be called by the user.
Computes post test probability to have a dissease based on the pre-test probability and the likelihood ratio of the diagnostic test
Description
This dialog box permits you to define the probability of a patient to have a disease before performing a diagnostic test (pre-test probability), and the likelihood ratio of the diagnostic test. Based on these two, the post-test probability to actually have the disease is computed.
This is computed the following way:
pre-test odds <- pre-test probability / (1 - pre-test probability)
post-test odds <- pre-test odds * likelihood ratio
post-test probability<- post-test odds / (post-test odds + 1)
Usage
fncEBMPostTest(.pretest, .LR)
Arguments
.pretest |
Pre-test probability. |
.LR |
Likekihood ratio of the diagnostic test. |
Value
The post-test probability of having the dissease.
Author(s)
Daniel-Corneliu Leucuta <danny.ldc@gmail.com>
Examples
fncEBMPostTest(.12, 5.7)