--- title: "Using loopnet: Directed Network Simulation and Feedback Analysis" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{Using loopnet} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```r # Load the loopnet package (after installation) library(loopnet) # Step 1: Create an undirected adjacency matrix (skeleton) adj <- matrix(0, 9, 9) adj[1, 2] <- adj[2, 1] <- 1 adj[2, 3] <- adj[3, 2] <- 1 adj[3, 4] <- adj[4, 3] <- 1 adj[4, 5] <- adj[5, 4] <- 1 adj[5, 6] <- adj[6, 5] <- 1 adj[6, 1] <- adj[1, 6] <- 1 # Step 2: Generate all possible directed networks nets <- generate_directed_networks(adj) length(nets) # Total configurations # Step 3: Select one network and detect feedback loops net1 <- nets[[1]] loops <- detect_feedback_loops(net1) str(loops) # Step 4: Compute overlap and topological features overlap <- compute_overlap_metrics(loops, n_nodes = nrow(adj)) topo <- summarize_topology(net1, loops) # Step 5: Simulate dynamics from this network params <- get_sample_parameters() S <- simulate_from_network(net1, params, t_max = 50) plot_symptom_dynamics(S) ``` This vignette walks through the end-to-end use of `loopnet`, from generating directed networks to simulating dynamic behavior and analyzing feedback loop structure.