Type: Package
Title: Generate and Simulate Deterministic Compartmental Models
Version: 1.2.2
Date: 2025-08-07
Description: R package to build and simulate deterministic compartmental models that can be non-Markovian. Length of stay in each compartment can be defined to follow a parametric distribution (d_exponential(), d_gamma(), d_weibull(), d_lognormal()) or a non-parametric distribution (nonparametric()). Other supported types of transition from one compartment to another includes fixed transition (constant()), multinomial (multinomial()), fixed transition probability (transprob()).
License: MIT + file LICENSE
URL: https://drthinhong.com/denim/, https://github.com/thinhong/denim
BugReports: https://github.com/thinhong/denim/issues
Depends: R (≥ 4.1.0)
Imports: Rcpp (≥ 1.0.6), colorspace, rlang, glue
Suggests: covr, knitr, rmarkdown, testthat (≥ 3.0.0), waldo, xml2, deSolve, tidyverse, DiagrammeR
LinkingTo: Rcpp, testthat
Encoding: UTF-8
RoxygenNote: 7.3.2
VignetteBuilder: knitr
Config/testthat/edition: 3
NeedsCompilation: yes
Packaged: 2025-08-21 04:28:49 UTC; anhptq
Author: Thinh Ong ORCID iD [aut, cph], Anh Phan ORCID iD [aut, cre], Marc Choisy ORCID iD [aut], Niels Lohman [ctb], Bjoern Hoehrmann [ctb], Florian Loitsch [ctb], Ingo Berg [ctb]
Maintainer: Anh Phan <anhptq@oucru.org>
Repository: CRAN
Date/Publication: 2025-08-21 08:40:18 UTC

denim

Description

Simulate deterministic model

Details

Imports

Author(s)

Maintainer: Anh Phan anhptq@oucru.org (ORCID)

Authors:

Other contributors:

See Also

Useful links:

Discrete exponential distribution

Description

Discrete exponential distribution

Usage

d_exponential(rate, dist_init = FALSE)

Arguments

rate

rate parameter of an exponential distribution

dist_init

whether to distribute initial value across subcompartments following this distribution. (default to FALSE, meaning init value is always in the first compartment)

Value

a Transition object for simulator

Examples

transitions <- list("I -> D" = d_exponential(0.3))
transitions <- denim_dsl({I -> D = d_exponential(0.3)})

Discrete gamma distribution

Description

Discrete gamma distribution

Usage

d_gamma(rate, shape, dist_init = FALSE)

Arguments

rate

rate parameter of a gamma distribution

shape

shape parameter of a gamma distribution

dist_init

whether to distribute initial value across subcompartments following this distribution.

Value

a Transition object for simulator

Examples

transitions <- list("S -> I" = d_gamma(rate = 1, shape = 5))
transitions_dsl <- denim_dsl({S -> I = d_gamma(rate = 1, shape = 5)})
# define model parameters as distributional parameters
transitions_dsl <- denim_dsl({S -> I = d_gamma(rate = i_rate, shape = i_shape)})

Discrete log-normal distribution

Description

Discrete log-normal distribution

Usage

d_lognormal(mu, sigma, dist_init = FALSE)

Arguments

mu

location parameter or the ln mean

sigma

scale parameter or ln standard deviation

dist_init

whether to distribute initial value across subcompartments following this distribution. (default to FALSE, meaning init value is always in the first compartment)

Value

a Transition object for simulator

Examples

transitions <- list("I -> D" = d_lognormal(3, 0.6))
transitions <- denim_dsl({I -> D = d_lognormal(3, 0.6)})

Discrete Weibull distribution

Description

Discrete Weibull distribution

Usage

d_weibull(scale, shape, dist_init = FALSE)

Arguments

scale

scale parameter of a Weibull distribution

shape

shape parameter of a Weibull distribution

dist_init

whether to distribute initial value across subcompartments following this distribution. (default to FALSE, meaning init value is always in the first compartment)

Value

a Transition object for simulator

Examples

transitions <- list("I -> D" = d_weibull(0.6, 2))
transitions <- denim_dsl({ I -> D = d_weibull(0.6, 2) })

Define transitions using denim's domain-specific language (DSL)

Description

This function parses model transitions defined in denim's DSL syntax

Usage

denim_dsl(x)

Arguments

x

  • an expression written in denim's DSL syntax. Each line should be a transition written in the format from -> to = transition where expression can be either a math expression or one of denim's built-in dwell time distribution function

Value

denim_transition object

Examples

transitions <- denim_dsl({
  S -> I = beta * (I/N) * S 
  I -> R = d_gamma(rate = 1/4, shape = 3)
})

Mathematical expression

Description

Mathematical expression

Usage

mathexpr(expr)

Arguments

expr

User defined mathematial expression. he expression will be processed by muparser library which offers a wide variety of operators. Visit muparser website (https://beltoforion.de/en/muparser/features.php) to see full list of available operators.

Value

a Transition object for simulator

Examples

transitions <- list("S->I"="beta*S/N")
transitions <- denim_dsl({S->I=beta*S/N})
# definition for parameters in the expression required
params <- c(N = 1000, beta = 0.3)

Nonparametric distribution transition

Description

Convert a vector of frequencies, percentages... into a distribution

Usage

nonparametric(x, dist_init = FALSE)

Arguments

x

a vector of values

dist_init

whether to distribute initial value across subcompartments following this distribution. (default to FALSE, meaning init value is always in the first compartment))

Value

a Transition object for simulator

Examples

transitions <- list("S->I"=nonparametric( c(0.1, 0.2, 0.5, 0.2) ))
transitions <- denim_dsl({S->I=nonparametric( c(0.1, 0.2, 0.5, 0.2) )})
# you can also define a model parameter for the distribution
transitions <- denim_dsl({S->I=nonparametric( dwelltime_dist )})

Overloaded plot function for denim object

Description

Overloaded plot function for denim object

Usage

## S3 method for class 'denim'
plot(x, ..., color_palette = NULL)

Arguments

x

  • output of denim::sim function

...

  • additional parameter for plot() function

color_palette

  • a palette name from the colorspace package. You can view available palettes with colorspace::hcl_palettes("qualitative", plot = TRUE).

Simulator for deterministic discrete time model with memory

Description

Simulation function that call the C++ simulator

Usage

sim(
  transitions,
  initialValues,
  parameters = NULL,
  simulationDuration,
  timeStep = 1,
  errorTolerance = 0.001
)

Arguments

transitions

output of function denim_dsl() or a list of transitions follows this format "transition" = expression

initialValues

a vector contains the initial values of all compartments defined in the transitions, follows this format compartment_name = initial_value

parameters

a vector contains values of any parameters that are not compartments, usually parameters used in mathexp() functions

simulationDuration

duration of time to be simulate

timeStep

set the output time interval. For example, if simulationDuration = 10 means 10 days and timeStep = 0.1, the output will display results for each 0.1 daily interval

errorTolerance

set the threshold so that a cumulative distribution function can be rounded to 1. For example, if we want a cumulative probability of 0.999 to be rounded as 1, we set errorTolerance = 0.001 (1 - 0.999 = 0.001). Default is 0.001

Value

a data.frame with class denim that can be plotted with a plot() method

Examples

# model can be defined using denim DSL
transitions <- denim_dsl({
   S -> I = beta * S * I / N
   I -> R = d_gamma(1/3, 2)
})

# or as a list
transitions <- list(
   "S -> I" = "beta * S * I / N",
   "I -> R" = d_gamma(1/3, 2)
)

initialValues <- c(
   S = 999, 
   I = 1, 
   R = 0
)

parameters <- c(
   beta = 0.012,
   N = 1000
)

simulationDuration <- 30
timeStep <- 0.01

mod <- sim(transitions = transitions, 
           initialValues = initialValues, 
           parameters = parameters, 
           simulationDuration = simulationDuration, 
           timeStep = timeStep)