

rpedgene (pedgene on CRAN)
Gene-level kernel and burden association tests of genetic variants
with a trait of interest, allowing for related individuals, including
twins.
Authors
Daniel J. Schaid and Jason P. Sinnwell Small contribution by A.
Visconti
Manuscript:
Schaid DJ,
McDonnell SK., Sinnwell JP, Thibodeau SN. (2013) Multiple
Genetic Variant Association Testing by Collapsing and Kernel Methods
With Pedigree or Population Structured Data Genet
Epidemiol, 37(5):409-18